Mechanical Characteristics of the Hard-Polydimethylsiloxane for Smart...
AbstractThis paper is a study about mechanical characteristics of hard-polydimethylsiloxane (h-PDMS), we compared and analyzed physical properties of h-PDMS with polydimethylsiloxane (PDMS) which in...
View ArticleFlavonoid glycosides from cowpea seeds (Vigna sinensis K.) inhibit LDL oxidation
AbstractSix flavonoid glycosides were isolated from the n-butanol fraction of cowpea seeds (Vigna sinensis K.) through silica gel (SiO2) and octadecyl silica gel (ODS) column chromatographies. Based on...
View ArticleTellimoside, a flavonol glycoside from Brasenia schreberi, inhibits the...
AbstractPrincipal components of aquatic plants responsible for inhibiting the growth of Microcystis aeruginosa, a blue-green alga (cyanobacterium) were determined. Methanol extracts of Brasenia...
View ArticleProcyanidins from the stem wood of Machilus japonica and their inhibitory...
AbstractThe stem wood of Machilus japonica Siebold & Zucc were extracted with 80 % aqueous MeOH, and the concentrated extract was successively partitioned with ethyl acetate (EtOAc), normal...
View ArticleLignans and neolignans from the stems of Vibrunum erosum and their...
AbstractA new lignan, (7′S,8S,8′S)-3,5′-dimethoxy-3′,4,9′-trihydroxy-7′,9-epoxy-8,8′-lignan, named vibruresinol (1), was isolated from the stems of Viburnum erosum by silica gel, ODS, and Sephadex...
View ArticlePhenylglycosides from the Stems of Spiraea prunifolia var. simpliciflora
One new phenylglycoside, 1-hydroxy-3,4,5-trimethoxyphenyl-1-O-[6′-O-(4″-carboxy-1″ ,3″ ,5″ - trihydroxy)phenyl]-β-D-glucopyranoside (1), along with eight known ones, isosalicin (2), vanilloloside (3),...
View ArticleFlavonoids from Fragaria ananassa calyx and their antioxidant capacities
AbstractThe calyx of Fragaria ananassa (Rosaceae) has not been investigated for its chemical constituents and biological activity. This study focused on the isolation of active metabolites from the...
View ArticleTNFR2 expression by CD4 effector T cells is required to induce full-fledged...
AbstractThere is now compelling evidence that TNFR2 is constitutively expressed on CD4+ Foxp3+ regulatory T cells (Tregs) and TNF-TNFR2 interaction is critical for the activation, expansion and...
View ArticleCorrection: Corrigendum: TNFR2 expression by CD4 effector T cells is required...
Scientific Reports 6: Article number: 32834; published online: 07 September 2016; updated: 13 October 2016
View ArticleNew Iridoid from the Stems of Viburnum erosum
A new iridoid (1) was isolated from the stems of Viburnum erosum along with two known iridoids, 7-O-tigloylsecologanolic acid (2) and 7-ketologanin (3). The chemical structure of the compounds was...
View ArticleLarge-scale pharmacogenomics based drug discovery for ITGB3 dependent...
AbstractEven when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed...
View ArticleMacrophage inducible nitric oxide synthase circulates inflammation and...
AbstractHuman lung squamous cell carcinoma (SCC) is highly associated with increased pulmonary macrophage infiltration. Previously, we showed that marked pulmonary infiltrating macrophages were...
View ArticleTargeting dysregulated lipid metabolism in the tumor microenvironment
AbstractThe reprogramming of lipid metabolism and its association with oncogenic signaling pathways within the tumor microenvironment (TME) have emerged as significant hallmarks of cancer. Lipid...
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